(Amazing X-Men I#4 (fb) - BTS) - During the early days of Apocalypse's reign, young Jamie Madrox's cloning powers were noticed by Mr. Sinister and Dark Beast who were always looking to improve on the potential of homo superior. En Sabah Nur saw use in Madrox's abilities to create copies of himself that were pliable, yet able to act independently of one another. He ordered Sinister and Beast to work on Madrox and after extensive experimentation Madrox was now able to spawn thousands of clones. As a result, he was left physically and mentally addled.
(X-Factor III#32 (fb) ) - Dark Beast used Jamie Madrox's cloning abilities to supply himself with an endless stream of test subjects for his often brutal experiments. McCoy called the poor, wiped out mutant "like the answer to a prayer".
(Amazing X-Men I#4 (fb) - BTS) - Apocalypse encouraged the army of Madrox clones to embrace his philosophies on the survival of the fittest. En Sabah Nur's teachings formed the basis of a new, extremist religious sect known as the Madri.
(Age of Apocalypse: The Chosen I#1 - BTS) - The Madri were tasked to be Apocalype's grand inquisitors. In his new world order, they served as his eyes and ears. The Madri were allowed free reign, moving around Apocalypse's realm without being questioned.
(Amazing X-Men I#4 (fb) - BTS)
- The Madri were stationed throughout Apocalypse's empire, but their
main temple was built in Quebec, Canada. There, the ailing Jamie Madrox
was cloistered away. Kept in a spartan cell with only building blocks
and other children's toys to keep him occupied, Madrox spent his days in
solitude, only seeing people when the Madri needed him to increase their
membership.(Amazing X-Men I#4 (fb) - BTS) - As the Madri spread their reign of terror, stories about their origins and the fate of Jamie Madrox began to spread, even reaching the X-Men.
(X-Calibre I#1 - BTS) - The Madri stationed at Apocalypse's citadel in what was once called New York City held regular prayer matins.
(X-Men Chronicles I#2 (fb) ) - The Madri were unable to oppose Magneto when he invaded their facilities to free the powerful mutant psionic Bennett Du Paris who they had been experimenting on.
(Blink I#1 - BTS) - Holocaust called on the perverted clergymen to help him beat back the invading forces of Negative Zone despot Blastaar and his army.
(Gambit & The X-Ternals I#1 - BTS) - Mudir Rictor led a contingent of Madri in a failed attempt to stop Gambit, his X-Ternals and Magneto from accessing one of Apocalypse's underground weapons caches.
(X-Calibre I#2 - BTS) - After Pale Riders member Danielle Moonstar informed Apocalypse's forces that the religious Ghost Dance faction was helping humans escape to Avalon, the Madri were sent to cleanse their compound inside the abandoned Stark Industries factory. The Madri massacred John Proudstar and his followers.
(X-Man I#2 - BTS) - A delegation of Madri were sent to cleanse a factory facility where human bone marrow was processed into a potential supplement to increase mutant powers. During their visit, the Madri had a run in with the powerful psionic Nate Grey who defeated all but one of the heavily armed zealots. The surviving Madri proceeded to inform Apocalypse of Grey's existence.
(Amazing X-Men I#1 &2 - BTS) - The Madri and the Brotherhood of Chaos accompanied Horseman Abyss to Maine to try and stop the Eurasian Human High Council's attempts to evacuate the surviving human population. When the Madri and the Broterhood failed in their mission, Abyss killed the Madri cardinal who actually thanked the Horseman for making him live up to Apocalypse's teachings.
(Amazing X-Men
I#3&4 - BTS) - The Madri and the Shadow King were tasked to
interrogate the mutant Bishop to access his memories of a timeline where
Apocalypse did not rule. Despite the Madri's torturous rituals that
lasted days, Bishop did not give up any pertinent information.(Age of Apocalypse: The Chosen I#1 - BTS) - One of the Madri accessed Apocalypse's restricted files on who En Sabah Nur deemed worthy of survival and who were destined to be forgotten. The Madri was overjoyed to learn his order was counted among the Chosen, but didn't realize Apocalypse had caught him snooping. The high lord made the Madri pay for his transgression by killing him on the spot and changing the entire order's designation to "Forgotten".
(Amazing X-Men I#4 - BTS) - The X-Men made it to the Madri temple in Quebec. While Storm singlehandedly freed Bishop from the zealots, Banshee and Quicksilver sneaked into the temple to look for Jamie Madrox. They moved in undetected thanks to Banshee's ability to knock out guards by using a hypersonic signal to scramble the fluids in their inner ear.
(Amazing X-Men I#4) - Quicksilver and Banshee were surprised to find the originator of the feared Madri was actually a delirious, soiled prisoner himself. Madrox, though drooling and glassy eyed, begged the X-Men for death. This made Banshee wonder if they had the right to kill a helpless man, even if it meant ending the threat of the Madri. Before they could continue their ethical discussion, Apocalypse's Horseman Abyss made his presence known. He had been tasked to oversee Bishop's questioning, but suspected the X-Men might try to reach Madrox. In the end, Banshee sacrificed himself so that Quicksilver could escape with Jamie.
(Amazing X-Men I#4) - Quicksilver managed to rush Madrox outside the Madri temple where Jamie, in a rare moment of clarity, decided to save Pietro from having to make that difficult life or death decision. Summoning every ounce of his strength, he assumed control over his untold copies and took back the "pieces of his soul" they took when they were spawned. The effort proved too much for him: he died in Quicksilver's arms and all the Madri instantly turned became lifeless husks.
(Age of Apocalypse I#4 - BTS)
- Years later, Sugar Man and Dark Beast recovered genetic material
from Jamie Madrox and dozens of other deceased mutants. They used
their DNA to create clones which the villains planned to properly
resurrect using energy they fed off of the Celestial lifeseed. Despite
the fact that they had three copies of Madrox available, they never
got around to reviving him before Humanity's Last Stand caused the
destruction of all the lifepods the clones were stored in.